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Try removing each component connected on these lines.
Remove ISL6259 before SMC; let it at the end.
C6952/53 and even corrosion under J6950/55 is possible.
Went throuth those one by one and was always about .18V difference SCL/SDA voltage drop.
Had to replace SMC again. Solved the SCA/SDL issue. 12.62V PPBUS. No Fan spin.
" S5_PWRGD is 3.4V
----------------------
PM_DSW_PWRGD,= 0v "
This could be SMC issue; check the Apple note ftom page 72.
Even PCH can pull down this signal; if has an internal damage.
Check all RTC signals at page 16.
YEs I read the note but wasn't sure if the RTC readings you requested were relevant to a bad PCH. I don't understand how the RTC signals are related to the diagnosing or if they would infer a damaged PCH as you also mentioned.
Old boards have 4 RTC DC signals for PCH.
PCH can start power on sequence without RTC clock, but NOT if one of the other 4 DC signals is not correct.
Nothe that, new PCH generations do not require PCH_INTVRMEN, nor PCH_INTRUDER_L signals.