For $29/mo, we provide access to advanced level technicians who will answer your questions on any Macbook board related matter to the best of their knowledge promptly & walk you through how to solve your problem so you can deliver a working board to your customer.
"Why would you want to have voltage on an active low enable signal?"
It was present on pin 2 Q7221 P5VS3_EN_L, but only because it's connected to PP3V42, right?
P5VS3_EN_L should be low (0V) to enable 5V_S3 power rail.
That's the reason I told you to remove Q7221.
In this way, both 3V and 5V sections of U7200 are always enabled.
"Check R/C7260, R7267/68 and Q7260/61."
I was refering to their integrity and correct value...
If all resistors and traces are OK around U7200, change the chip.
Post resistance to ground at L7260; diode mode, both ways (red and black to ground).
Maybe Q7260/61 need to be changed too.
0.033 in diode mode is aprox 60 ohms.
Usually you cannot heat anything with 5V there.
But you can try, maybe some IC enter in avalanche process and overheats...
First remove U5850 and test again.
I found bad keyboard backlight circuit few times.